Explore Your AAV Vector Design Space

Broaden your vector design horizons using intuitive tools that harness AI/ML models trained on AAV vector nucleotide sequences.

Design for Safety

Numerous studies have shown immunogenicity of empty capsids in humans (ref 1 & 2). Researchers have several avenues to reduce the innate immunogenicity of vector plasmids. Form Bio facilitates in silico vector design iterations to enhance drug safety by minimizing empty and partial capsids, predicting CpG islands, assessing truncation propensity and evaluating secondary and tertiary structures—thus mitigating adaptive immune responses.